Our company has a strict QA&QC system and all of
products are in line with the USP32 standard as well as enterprise
internal control standard. Our high tech laboratory
also own several sets of analyzing instruments with high efficiency
and high sensitivity, such as HPLC, GC and UV spectrometer to
analyze and control the products.
HPLC-MS. High pressure liquid chromatography coupled with mass
spectrometry is a powerful method which we also routinely use for
identity and purity checking. It gives quantitative measure of
compound purity along with the measurement of its molecular weight.
MS-ESI. Electrospray ionization mass spectrometry can test the molecular
weight of the object.
NMR. Nuclear magnetic resonance is the basic method for the
identification of organic compounds. We routinely use 1H NMR for identity and purity checking. For phosphoramidites and
triphosphates, 31P NMR is used, too. And we also measure other nuclei (13C,19F, etc) for all compounds which we prepare for the first time to
identify them unambiguously. Two-dimensional NMR (such as HSQC and
HMBC) are used for complicated cases. For example, we attributed
rhodamine isomers with 2D NMR - something impossible to do with
one-dimensional NMR spectra.